Can CRISPRa solve aging?
CRISPR activation (CRISPRa) activates endogenous genes. In a recent study they showed how this works to activate Yamanaka factors & other sites to promote cellular reprogramming.
The future method to rejuvenate fertility?
In vitro gametogenesis - growing egg and sperm in a dish - could be an interesting therapeutic approach to tackle the "fertility crisis"
3 rejuvenation strategies
Heterochronic transplants, cellular reprogramming and natural rejuvenation.
Until recently ~8% of the human genome sequence was missing. It is now sequenced - yay!
But, what information does the human genome sequence actually tell us - is it the 'book of life' as you may hear it described?
Why did it take us so long to get the full sequence, how was it done? What are the consequences or next steps now we have the full sequence.
These are just a few of the questions i raise and discuss in this video.